Updated September 2026

Infection Control CNA Practice Test 2 with Answers

Get ready for your 2026 CNA written exam with infection control questions that feel like real test-day scenarios. This practice set focuses on the rules CNAs use every day: hand hygiene, PPE selection, isolation precautions, and preventing the spread of infection.

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This Infection Control Practice Test Is Built for Real CNA Judgment

Mastering infection control—handwashing technique, preventing the spread of germs, understanding transmission routes, and selecting the right PPE—is essential in your role as a CNA. Our nursing educators designed this self-paced practice test to help you understand the “why” behind every infection prevention step, with instant feedback on every question.

To make sure you’re prepared for the real thing, our Registered Nurses personally vet all content to meet 2026 NNAAP standards. We update our question bank regularly, providing the same high-quality prep that over 50,000 students trust every year to pass their state exams and start their healthcare careers with confidence.

Medically reviewed by:

Michele J. McCarthy, RN, MSN, CNE, medical reviewer

Michele J. McCarthy

RN, MSN, CNE

Kailey R. CNA Instructor

Kailey R.

CNA Instructor

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Common Questions About Infection Control on the CNA Exam

These FAQs help you choose the safest CNA answer by focusing on the best practices of infection control—from hand hygiene timing to isolation precautions.

What infection control topics show up most on the CNA exam?

Hand hygiene timing, gloves and PPE use, isolation precautions, the clean-to-dirty principle, handling soiled linens, and preventing cross-contamination with shared equipment. These topics are central to CNA practice, so they appear often on both the written exam and the skills portion.

When should I wash my hands instead of using hand sanitizer?

Use soap and water when your hands are visibly soiled, after exposure to blood or body fluids, or when the question is clearly asking for the safest option. On the exam, when it asks “What should you do next after removing gloves?” or a similar question, handwashing is usually the best answer.

If I wear gloves, do I still need to perform hand hygiene?

Yes. Gloves do not replace hand hygiene. You still need to wash or sanitize your hands after removing gloves and before moving on to clean tasks or touching clean supplies. Think of gloves as a protective barrier—they reduce exposure, but germs must still be removed.

What does ‘clean to dirty’ mean in simple terms?

Always work from the cleanest area to the dirtiest. This prevents germs from spreading to surfaces that are still clean. For example, when bathing a resident, wash the face first and the perineal area last.

What’s the most common mistake on infection control questions?

Touching clean items after a dirty task without performing hand hygiene first. On the written exam and during the skills portion, any time you move from a dirty task to a clean one, hand hygiene is required before you touch anything clean.

What’s the safest way to handle soiled linens?

Do not shake them. Hold them away from your uniform, handle them from the edges, and place them directly into the correct bag or hamper according to facility policy. Shaking linens spreads airborne contaminants.

What should I do if blood or body fluids get on me?

Stop and address it immediately. Safely remove any contaminated PPE or clothing, wash the exposed area thoroughly, and report the exposure to the nurse according to facility policy. On the exam, look for answers that include both immediate cleaning and reporting to the nurse—not ignoring or delaying.

How do I choose between two answers that both seem correct?

Prioritize CNA infection control responsibilities in this order:

  • Prevent the spread of infection (proper hand hygiene and correct PPE use)
  • Protect resident safety (clean-to-dirty order, safe disposal of waste)
  • Follow isolation precautions (rules and signage for the specific precaution type)
  • Report exposures or unsafe situations to the nurse

When two answers seem right, ask: “Which option best prevents infection and protects the resident, within the CNA role?” That’s usually the strongest choice.

Can I take this practice test on my phone?

Yes. The quiz works on mobile, tablet, and desktop.

How many questions are on this practice test?

This quiz includes 20 multiple-choice questions.

Is there a time limit?

No—complete it at your own pace.

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