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HESI A2 Chemistry Practice Test With Answers

Strengthen the chemistry fundamentals that show up in HESI-style questions, such as atomic structure, periodic trends, mixtures and solutions, reaction basics, and simple calculations that test accuracy more than speed.

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What This Chemistry Practice Test Helps You Fix

Chemistry questions get easier when you focus on the concept first, then the math. Most mistakes are from not knowing a definition, skipping units, or rushing through basic relationships such as pH, concentration, and reaction patterns.

This practice set helps you build strong test taking skills by training you to identify what the question is testing, eliminate close distractors, and choose the answer that fits the rule without extra assumptions.

This page was reviewed by:

Tabitha C. HESI Instructor

Tabitha C.

HESI Instructor

Molly W., Registered Nurse

Molly W.

Registered Nurse

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Common Questions About the HESI A2 Chemistry Test

Quick answers about the chemistry topics most students miss and how to approach them without overthinking.

What chemistry topics matter most for HESI A2 style questions?

Focus on atoms and ions, bonding basics, periodic table patterns, reaction types, solutions, and acids and bases.

Do I need to memorize the entire periodic table?

No. You need to understand the structure, common trends, and how to use the table to compare elements.

Are chemistry questions more math-heavy or concept-heavy?

Usually concept-heavy with light calculations. Clean fundamentals and careful reading matter more than complex math.

How do I avoid mistakes on concentration and solution questions?

Track units, write the relationship you are using, and double-check decimals before you choose an answer.

What is the best way to study acids and bases for this level?

Know pH basics, strong vs weak, and what happens when acids and bases react. Then practice a small set until the pattern feels automatic.

What should I do when two answers look correct?

Choose the option that matches the definition or rule being tested the best. Wrong choices often sound close but ignore one key detail.

Should I retake this chemistry set more than once?

Yes. Retake it after a short gap to confirm you learned the concept rather than memorizing the answers.

What should I do if I keep missing the same chemistry topic?

Stop and drill that topic alone for 15 to 20 minutes, then retest. Most chemistry improvement comes from fixing repeat patterns.

Do I need to balance equations for the HESI A2 Chemistry section?

At this level, you should understand what balancing means and be comfortable with simple examples, but the focus is usually on core concepts and basic relationships, not long, messy equations.

What’s the easiest way to handle oxidation and reduction questions?

Track electrons in plain language: oxidation loses electrons, reduction gains electrons. If that feels confusing, use the quick memory trick “OIL RIG” and practice a few items until it clicks.

Are stoichiometry questions common on the HESI A2?

They can appear, but usually in a light form. Expect simple mole or ratio logic rather than multi-step problems.

How deep do I need to go with gas laws?

Know the basic idea of how pressure, volume, and temperature relate. If you can explain the direction of change, you’re already ahead.